#------------------------------------------------------------------------------ #$Date: 2025-08-18 23:52:38 +0100 (Mon, 18 Aug 2025) $ #$Revision: 301791 $ #$URL: svn://www.crystallography.net/cod/cif/2/00/65/2006560.cif $ #------------------------------------------------------------------------------ # # This file is available in the Crystallography Open Database (COD), # http://www.crystallography.net/. The original data for this entry # were provided by IUCr Journals, http://journals.iucr.org/. # # The file may be used within the scientific community so long as # proper attribution is given to the journal article from which the # data were obtained. # data_2006560 loop_ _publ_author_name 'Deschamps, Jeffrey R.' 'Flippen-Anderson, Judith L.' 'Christi Moore' 'Robert Cudney' 'George, Clifford' _publ_section_title ; Tyrosinium-D-tetrahydroisoquinoline-3-carboxylate 1.5-Hydrate and Tyrosyl-D-tetrahydroisoquinoline-3-carboxamide Hydrate ; _journal_issue 10 _journal_name_full 'Acta Crystallographica Section C' _journal_page_first 1478 _journal_page_last 1482 _journal_paper_doi 10.1107/S0108270197006975 _journal_volume 53 _journal_year 1997 _chemical_formula_moiety 'C19 H20 N2 O4,1.5H2 O' _chemical_formula_sum 'C19 H23 N2 O5.5' _chemical_formula_weight 367.39 _chemical_name_common ; Tyr-D-Tic ; _chemical_name_systematic ; tyrosyl-D-tetrahydroisoquinoline-3-carboxylic acid ; _space_group_IT_number 19 _symmetry_cell_setting orthorhombic _symmetry_space_group_name_Hall 'P 2ac 2ab' _symmetry_space_group_name_H-M 'P 21 21 21' _audit_creation_method SHELXL _cell_angle_alpha 90.00 _cell_angle_beta 90.00 _cell_angle_gamma 90.00 _cell_formula_units_Z 8 _cell_length_a 9.1270(10) _cell_length_b 10.5220(10) _cell_length_c 37.195(2) _cell_measurement_reflns_used 35 _cell_measurement_temperature 223(2) _cell_measurement_theta_max 59.894 _cell_measurement_theta_min 9.630 _cell_volume 3572.0(6) _computing_cell_refinement XSCANS _computing_data_collection 'XSCANS (Siemens, 1994)' _computing_data_reduction XSCANS _computing_molecular_graphics SHELXTL _computing_publication_material SHELXTL _computing_structure_refinement SHELXTL _computing_structure_solution 'SHELXTL (Sheldrick, 1994)' _diffrn_ambient_temperature 223(2) _diffrn_measurement_device 'Siemens P4' _diffrn_measurement_method '2\q/\w scans' _diffrn_radiation_monochromator graphite _diffrn_radiation_source 'sealed tube' _diffrn_radiation_type CuK\a _diffrn_radiation_wavelength 1.54178 _diffrn_reflns_av_R_equivalents 0.0217 _diffrn_reflns_av_sigmaI/netI 0.0468 _diffrn_reflns_limit_h_max 9 _diffrn_reflns_limit_h_min -1 _diffrn_reflns_limit_k_max 11 _diffrn_reflns_limit_k_min 0 _diffrn_reflns_limit_l_max 40 _diffrn_reflns_limit_l_min 0 _diffrn_reflns_number 3258 _diffrn_reflns_theta_max 57.00 _diffrn_reflns_theta_min 2.38 _diffrn_standards_decay_% 2.01 _diffrn_standards_interval_count 97 _diffrn_standards_number 3 _exptl_absorpt_coefficient_mu 0.838 _exptl_absorpt_correction_T_max 0.95 _exptl_absorpt_correction_T_min 0.72 _exptl_absorpt_correction_type 'face-indexed numerical' _exptl_crystal_colour 'clear colorless' _exptl_crystal_density_diffrn 1.366 _exptl_crystal_density_method 'not measured' _exptl_crystal_description plate _exptl_crystal_F_000 1560 _exptl_crystal_size_max 0.56 _exptl_crystal_size_mid 0.35 _exptl_crystal_size_min 0.06 _refine_diff_density_max 0.459 _refine_diff_density_min -0.233 _refine_ls_abs_structure_details 'Flack (1983)' _refine_ls_abs_structure_Flack 0.0(3) _refine_ls_extinction_coef 0.0013(2) _refine_ls_extinction_method 'SHELXL93 (Sheldrick, 1993)' _refine_ls_goodness_of_fit_all 1.063 _refine_ls_goodness_of_fit_obs 1.083 _refine_ls_hydrogen_treatment 'H atoms: coordinates only' _refine_ls_matrix_type full _refine_ls_number_parameters 511 _refine_ls_number_reflns 3105 _refine_ls_number_restraints 74 _refine_ls_restrained_S_all 1.062 _refine_ls_restrained_S_obs 1.082 _refine_ls_R_factor_all 0.0529 _refine_ls_R_factor_obs .0458 _refine_ls_shift/esd_max -0.089 _refine_ls_shift/esd_mean 0.004 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w = 1/[\s^2^(Fo^2^)+(0.0866P)^2^+0.2685P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_all 0.1267 _refine_ls_wR_factor_obs .1207 _reflns_number_observed 2770 _reflns_number_total 3105 _reflns_observed_criterion >2\s(I) _cod_data_source_file bs1028.cif _cod_data_source_block 1 _cod_depositor_comments ; Marking attached hydrogen atoms. Antanas Vaitkus, 2017-11-23 The following automatic conversions were performed: '_geom_torsion_publ_flag' value 'Y' changed to 'y' according to /home/saulius/struct/CIF-dictionaries/cif_core.dic dictionary named 'cif_core.dic' version 2.4.1 from 2010-06-29 (20 times). Automatic conversion script Id: cif_fix_values 1715 2011-07-08 13:25:40Z adriana The following automatic conversions were performed: '_refine_ls_weighting_scheme' value 'calc w = 1/[\s^2^(Fo^2^)+(0.0866P)^2^+0.2685P] where P=(Fo^2^+2Fc^2^)/3' was changed to 'calc'. New tag '_refine_ls_weighting_details' was created. The value of the new tag was set to 'w = 1/[\s^2^(Fo^2^)+(0.0866P)^2^+0.2685P] where P=(Fo^2^+2Fc^2^)/3'. Automatic conversion script Id: cif_fix_values 3143 2015-03-26 13:38:13Z robertas ; _cod_original_formula_sum 'C19 H23 N2 O5.50' _cod_database_code 2006560 loop_ _symmetry_equiv_pos_as_xyz 'x, y, z' '-x+1/2, -y, z+1/2' '-x, y+1/2, -z+1/2' 'x+1/2, -y+1/2, -z' loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_12 _atom_site_aniso_U_13 _atom_site_aniso_U_23 N1 .030(2) .031(2) .029(2) .001(2) .002(2) .008(2) C1A .029(2) .023(2) .025(2) -.005(2) .001(2) .007(2) C1' .021(2) .029(2) .022(2) .001(2) -.007(2) .001(2) O1 .043(2) .041(2) .033(2) .006(2) .012(2) .0040(14) C1B .043(3) .035(3) .039(2) -.013(3) -.011(2) .009(2) C1G .032(2) .029(2) .036(2) -.009(2) -.010(2) .000(2) C1D1 .042(3) .031(2) .044(3) .006(2) -.014(2) -.001(2) C1E1 .044(3) .034(2) .035(2) .008(3) -.007(2) -.008(2) C1Z .036(3) .026(2) .033(2) -.004(2) -.010(2) .001(2) C1E2 .034(3) .025(2) .041(3) -.001(2) -.008(2) -.002(2) C1D2 .030(3) .035(3) .035(2) -.001(2) -.003(2) -.007(2) O1Z .052(2) .029(2) .032(2) .006(2) -.008(2) .0022(13) N2 .026(2) .019(2) .031(2) -.001(2) .004(2) -.003(2) C2A .026(2) .024(2) .034(2) .002(2) -.002(2) -.007(2) C2' .036(3) .030(3) .030(2) -.003(2) -.002(2) -.005(2) O2 .051(2) .024(2) .065(2) -.007(2) -.012(2) .002(2) O2' .031(2) .032(2) .055(2) -.001(2) -.012(2) -.005(2) C2B .032(3) .031(2) .056(3) .003(2) -.008(2) -.003(2) C2G .030(3) .037(3) .041(3) -.006(2) -.012(2) .001(2) C2D .031(3) .028(2) .036(2) -.011(2) -.005(2) .002(2) C2E .034(3) .024(2) .037(2) .000(2) .010(2) .005(2) C2G1 .044(3) .057(3) .059(3) .002(3) -.021(3) .016(3) C2G2 .057(4) .076(4) .045(3) -.009(4) -.022(3) .021(3) C2G3 .049(3) .080(4) .035(3) -.015(4) -.007(3) .006(3) C2G4 .038(3) .047(3) .035(2) -.012(3) -.001(2) -.002(2) N3 .021(2) .026(2) .023(2) .002(2) -.005(2) .004(2) C3A .018(2) .023(2) .025(2) .002(2) -.005(2) .000(2) C3' .023(2) .016(2) .020(2) -.001(2) -.006(2) .005(2) O3 .030(2) .030(2) .0290(15) -.0015(15) -.0031(14) -.0085(13) C3B .023(2) .035(2) .035(2) -.010(2) -.007(2) .009(2) C3G .024(2) .024(2) .030(2) -.010(2) -.005(2) .008(2) C3D1 .025(2) .027(2) .036(2) .003(2) -.002(2) .008(2) C3E1 .036(3) .025(2) .029(2) .001(2) .001(2) .001(2) C3Z .026(2) .020(2) .028(2) -.002(2) -.006(2) .005(2) C3E2 .028(2) .019(2) .033(2) .005(2) -.004(2) .004(2) C3D2 .033(3) .023(2) .029(2) -.002(2) .000(2) .000(2) O3Z .045(2) .031(2) .033(2) .006(2) -.011(2) .0003(14) N4 .017(2) .020(2) .024(2) -.001(2) .0015(15) -.0025(15) C4A .017(2) .025(2) .029(2) -.001(2) .001(2) -.005(2) C4' .027(3) .029(2) .027(2) .002(2) .002(2) -.002(2) O4 .030(2) .036(2) .047(2) -.005(2) -.002(2) .013(2) O4' .020(2) .034(2) .044(2) -.0043(15) -.0029(15) -.0024(14) C4B .021(2) .025(2) .040(2) .003(2) -.002(2) -.001(2) C4G .022(2) .020(2) .037(2) -.003(2) .000(2) .003(2) C4D .021(2) .022(2) .027(2) -.006(2) -.002(2) .003(2) C4E .020(2) .021(2) .028(2) .002(2) -.002(2) -.006(2) C4G1 .035(3) .032(2) .042(3) -.001(2) -.008(2) .008(2) C4G2 .038(3) .045(3) .042(3) -.001(3) -.018(2) .013(2) C4G3 .057(3) .040(3) .030(2) -.012(3) -.009(3) .002(2) C4G4 .037(3) .025(2) .034(2) -.004(2) -.003(2) .000(2) O1S .043(2) .042(2) .067(2) .002(2) -.009(2) .009(2) O2S .059(3) .033(2) .090(3) -.008(2) -.027(3) .014(2) O3S .051(3) .057(3) .146(4) .005(2) .021(3) .011(3) loop_ _atom_site_label _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_thermal_displace_type _atom_site_calc_flag _atom_site_refinement_flags _atom_site_occupancy _atom_site_disorder_group _atom_site_type_symbol _atom_site_attached_hydrogens N1 .1072(5) .2240(4) .11217(10) .0301(9) Uani d . 1 . N 0 H1B .048(6) .198(5) .1287(13) .036 Uiso d . 1 . H 0 H1C .176(6) .153(5) .1060(11) .036 Uiso d . 1 . H 0 H1D .171(6) .267(5) .1271(12) .036 Uiso d . 1 . H 0 C1A .0563(5) .2911(4) .07920(10) .0258(10) Uani d . 1 . C 0 H1A .1360(5) .2935(4) .06156(10) .028 Uiso calc R 1 . H 0 C1' .0159(5) .4258(4) .08988(10) .0242(10) Uani d . 1 . C 0 O1 -.0647(4) .4403(3) .11620(8) .0391(8) Uani d . 1 . O 0 C1B -.0790(6) .2260(5) .06229(11) .0390(12) Uani d . 1 . C 0 H1B1 -.0593(6) .1360(5) .05916(11) .043 Uiso calc R 1 . H 0 H1B2 -.1621(6) .2345(5) .07835(11) .043 Uiso calc R 1 . H 0 C1G -.1159(5) .2845(4) .02632(11) .0323(11) Uani d . 1 . C 0 C1D1 -.0595(6) .2350(5) -.00523(12) .0386(12) Uani d . 1 . C 0 H1D1 -.0015(6) .1624(5) -.00422(12) .043 Uiso calc R 1 . H 0 C1E1 -.0868(6) .2905(4) -.03815(12) .0378(11) Uani d . 1 . C 0 H1E1 -.0478(6) .2552(4) -.05897(12) .042 Uiso calc R 1 . H 0 C1Z -.1728(5) .3994(4) -.04013(11) .0317(11) Uani d . 1 . C 0 C1E2 -.2315(5) .4512(4) -.00899(12) .0331(11) Uani d . 1 . C 0 H1E2 -.2894(5) .5239(4) -.01010(12) .036 Uiso calc R 1 . H 0 C1D2 -.2030(5) .3937(4) .02372(12) .0332(11) Uani d . 1 . C 0 H1D2 -.2426(5) .4286(4) .04453(12) .037 Uiso calc R 1 . H 0 O1Z -.1995(4) .4480(3) -.07389(7) .0375(8) Uani d . 1 . O 0 H1ZA -.2536(4) .5100(3) -.07224(7) .056 Uiso calc R 1 . H 0 N2 .0667(4) .5229(3) .07038(9) .0256(8) Uani d . 1 . N 0 C2A .0242(5) .6547(4) .07899(11) .0278(10) Uani d . 1 . C 0 H2A -.0442(5) .6510(4) .09928(11) .031 Uiso calc R 1 . H 0 C2' .1567(5) .7331(4) .09109(11) .0321(11) Uani d . 1 . C 0 O2 .1497(4) .8500(3) .08501(9) .0466(9) Uani d . 1 . O 0 O2' .2595(4) .6792(3) .10770(9) .0393(8) Uani d . 1 . O 0 C2B -.0574(5) .7111(5) .04756(12) .0396(12) Uani d . 1 . C 0 H2B1 -.0665(5) .8020(5) .05119(12) .044 Uiso calc R 1 . H 0 H2B2 -.1554(5) .6756(5) .04690(12) .044 Uiso calc R 1 . H 0 C2G .0162(5) .6873(4) .01171(12) .0362(12) Uani d . 1 . C 0 C2D .1134(5) .5868(4) .00749(11) .0314(11) Uani d . 1 . C 0 C2E .1652(5) .5111(4) .03914(11) .0319(10) Uani d . 1 . C 0 H2E1 .1722(5) .4223(4) .03231(11) .035 Uiso calc R 1 . H 0 H2E2 .2624(5) .5397(4) .04589(11) .035 Uiso calc R 1 . H 0 C2G1 -.0205(6) .7581(6) -.01863(14) .0531(15) Uani d . 1 . C 0 H2G1 -.0841(6) .8267(6) -.01639(14) .058 Uiso calc R 1 . H 0 C2G2 .0362(7) .7279(6) -.05202(14) .059(2) Uani d . 1 . C 0 H2G2 .0128(7) .7775(6) -.07190(14) .065 Uiso calc R 1 . H 0 C2G3 .1256(6) .6264(6) -.05580(13) .055(2) Uani d . 1 . C 0 H2G3 .1599(6) .6041(6) -.07848(13) .060 Uiso calc R 1 . H 0 C2G4 .1657(6) .5563(5) -.02639(11) .0399(12) Uani d . 1 . C 0 H2G4 .2287(6) .4875(5) -.02919(11) .044 Uiso calc R 1 . H 0 N3 .3841(4) .8894(4) .14114(9) .0234(8) Uani d . 1 . N 0 H3B .293(6) .921(5) .1435(11) .028 Uiso d . 1 . H 0 H3C .372(5) .824(5) .1268(12) .028 Uiso d . 1 . H 0 H3D .424(5) .947(4) .1228(12) .028 Uiso d . 1 . H 0 C3A .4707(4) .8657(4) .17453(10) .0218(9) Uani d . 1 . C 0 H3A .4704(4) .9419(4) .18968(10) .024 Uiso calc R 1 . H 0 C3' .6266(4) .8352(4) .16277(10) .0198(9) Uani d . 1 . C 0 O3 .6419(3) .7598(3) .13747(7) .0298(7) Uani d . 1 . O 0 C3B .4046(5) .7544(4) .19504(11) .0308(10) Uani d . 1 . C 0 H3B1 .3025(5) .7725(4) .20011(11) .034 Uiso calc R 1 . H 0 H3B2 .4084(5) .6790(4) .18004(11) .034 Uiso calc R 1 . H 0 C3G .4836(5) .7278(4) .23003(10) .0263(10) Uani d . 1 . C 0 C3D1 .4445(5) .7939(4) .26155(11) .0290(10) Uani d . 1 . C 0 H3D1 .3664(5) .8507(4) .26103(11) .032 Uiso calc R 1 . H 0 C3E1 .5201(5) .7754(4) .29300(11) .0298(10) Uani d . 1 . C 0 H3E1 .4941(5) .8209(4) .31344(11) .033 Uiso calc R 1 . H 0 C3Z .6349(5) .6895(4) .29460(10) .0248(10) Uani d . 1 . C 0 C3E2 .6743(5) .6232(4) .26376(10) .0267(10) Uani d . 1 . C 0 H3E2 .7516(5) .5657(4) .26446(10) .029 Uiso calc R 1 . H 0 C3D2 .5987(5) .6427(4) .23209(10) .0282(10) Uani d . 1 . C 0 H3D2 .6258(5) .5975(4) .21166(10) .031 Uiso calc R 1 . H 0 O3Z .7050(4) .6740(3) .32683(7) .0362(8) Uani d . 1 . O 0 H3ZA .7706(4) .6213(3) .32460(7) .054 Uiso calc R 1 . H 0 N4 .7400(4) .8896(3) .17963(8) .0207(8) Uani d . 1 . N 0 C4A .8898(5) .8617(4) .16787(10) .0238(9) Uani d . 1 . C 0 H4A .8833(5) .8144(4) .14525(10) .026 Uiso calc R 1 . H 0 C4' .9747(5) .9841(4) .16036(11) .0277(10) Uani d . 1 . C 0 O4 .9039(4) 1.0766(3) .14765(8) .0377(8) Uani d . 1 . O 0 O4' 1.1103(3) .9837(3) .16634(8) .0325(7) Uani d . 1 . O 0 C4B .9588(5) .7744(4) .19571(11) .0286(10) Uani d . 1 . C 0 H4B1 .9087(5) .6931(4) .19558(11) .031 Uiso calc R 1 . H 0 H4B2 1.0607(5) .7597(4) .18960(11) .031 Uiso calc R 1 . H 0 C4G .9492(5) .8324(4) .23263(11) .0264(10) Uani d . 1 . C 0 C4D .8409(5) .9234(4) .24038(10) .0232(9) Uani d . 1 . C 0 C4E .7318(5) .9667(4) .21252(10) .0233(9) Uani d . 1 . C 0 H4E1 .6337(5) .9610(4) .22243(10) .026 Uiso calc R 1 . H 0 H4E2 .7505(5) 1.0550(4) .20658(10) .026 Uiso calc R 1 . H 0 C4G1 1.0440(6) .7953(5) .25999(12) .0363(11) Uani d . 1 . C 0 H4G1 1.1148(6) .7340(5) .25519(12) .040 Uiso calc R 1 . H 0 C4G2 1.0359(6) .8467(5) .29393(13) .0415(13) Uani d . 1 . C 0 H4G2 1.1015(6) .8213(5) .31168(13) .046 Uiso calc R 1 . H 0 C4G3 .9283(6) .9375(5) .30151(12) .0420(13) Uani d . 1 . C 0 H4G3 .9218(6) .9733(5) .32431(12) .046 Uiso calc R 1 . H 0 C4G4 .8320(5) .9733(4) .27474(11) .0320(11) Uani d . 1 . C 0 H4G4 .7592(5) 1.0324(4) .27993(11) .035 Uiso calc R 1 . H 0 O1S .5991(4) 1.0948(4) .12844(10) .0506(10) Uani d D 1 . O 0 H1SA .681(4) 1.096(6) .1423(13) .066 Uiso d D 1 . H 0 H1SB .556(6) 1.166(3) .1206(13) .066 Uiso d D 1 . H 0 O2S .3235(5) .4228(4) .11901(13) .0609(12) Uani d D 1 . O 0 H2SA .315(11) .5079(15) .118(2) .14(4) Uiso d D 1 . H 0 H2SB .4220(16) .420(9) .121(2) .13(3) Uiso d D 1 . H 0 O3S .6337(5) .4851(4) .13460(15) .085(2) Uani d . 1 . O 2 loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0181 0.0091 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' N N 0.0311 0.0180 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0492 0.0322 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' Cl Cl 0.3639 0.7018 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle N1 C1A C1' 107.6(3) N1 C1A C1B 111.9(3) C1' C1A C1B 109.1(4) O1 C1' N2 122.9(4) O1 C1' C1A 117.9(4) N2 C1' C1A 119.2(4) C1G C1B C1A 110.9(4) C1D1 C1G C1D2 117.5(4) C1D1 C1G C1B 120.9(4) C1D2 C1G C1B 121.5(4) C1E1 C1D1 C1G 121.8(4) C1D1 C1E1 C1Z 119.9(4) O1Z C1Z C1E2 123.1(4) O1Z C1Z C1E1 117.0(4) C1E2 C1Z C1E1 119.8(4) C1D2 C1E2 C1Z 119.3(4) C1E2 C1D2 C1G 121.8(4) C1' N2 C2E 125.1(3) C1' N2 C2A 120.6(3) C2E N2 C2A 114.2(3) N2 C2A C2B 109.4(3) N2 C2A C2' 111.2(4) C2B C2A C2' 113.9(4) O2 C2' O2' 124.7(5) O2 C2' C2A 115.8(4) O2' C2' C2A 119.4(4) C2A C2B C2G 113.5(4) C2D C2G C2G1 118.0(5) C2D C2G C2B 120.5(4) C2G1 C2G C2B 121.3(4) C2G4 C2D C2G 119.9(4) C2G4 C2D C2E 118.9(4) C2G C2D C2E 121.2(4) N2 C2E C2D 112.5(4) C2G2 C2G1 C2G 121.0(5) C2G3 C2G2 C2G1 120.1(5) C2G2 C2G3 C2G4 120.3(5) C2G3 C2G4 C2D 120.6(5) N3 C3A C3' 106.9(3) N3 C3A C3B 109.6(3) C3' C3A C3B 110.6(3) O3 C3' N4 122.8(4) O3 C3' C3A 117.3(3) N4 C3' C3A 119.9(3) C3G C3B C3A 112.6(3) C3D2 C3G C3D1 117.8(4) C3D2 C3G C3B 121.9(4) C3D1 C3G C3B 120.2(4) C3E1 C3D1 C3G 120.7(4) C3D1 C3E1 C3Z 120.7(4) O3Z C3Z C3E1 118.0(4) O3Z C3Z C3E2 122.8(4) C3E1 C3Z C3E2 119.2(4) C3D2 C3E2 C3Z 120.0(4) C3E2 C3D2 C3G 121.5(4) C3' N4 C4A 119.8(3) C3' N4 C4E 125.9(3) C4A N4 C4E 114.0(3) N4 C4A C4B 107.7(3) N4 C4A C4' 111.0(3) C4B C4A C4' 115.1(3) O4' C4' O4 125.0(4) O4' C4' C4A 117.7(4) O4 C4' C4A 117.4(4) C4G C4B C4A 110.6(3) C4G1 C4G C4D 118.6(4) C4G1 C4G C4B 121.1(4) C4D C4G C4B 120.3(4) C4G4 C4D C4G 119.3(4) C4G4 C4D C4E 118.7(4) C4G C4D C4E 122.0(4) N4 C4E C4D 111.8(3) C4G2 C4G1 C4G 121.8(5) C4G1 C4G2 C4G3 119.4(4) C4G4 C4G3 C4G2 119.2(4) C4G3 C4G4 C4D 121.6(5) loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_site_symmetry_2 _geom_bond_distance _geom_bond_publ_flag N1 C1A . 1.489(5) ? C1A C1' . 1.518(6) ? C1A C1B . 1.546(6) ? C1' O1 . 1.234(5) ? C1' N2 . 1.336(5) ? C1B C1G . 1.511(6) ? C1G C1D1 . 1.384(6) ? C1G C1D2 . 1.400(6) ? C1D1 C1E1 . 1.379(6) ? C1E1 C1Z . 1.391(6) ? C1Z O1Z . 1.378(5) ? C1Z C1E2 . 1.388(6) ? C1E2 C1D2 . 1.384(6) ? N2 C2E . 1.474(5) ? N2 C2A . 1.475(5) ? C2A C2B . 1.508(6) ? C2A C2' . 1.532(6) ? C2' O2 . 1.252(6) ? C2' O2' . 1.258(6) ? C2B C2G . 1.514(7) ? C2G C2D . 1.390(6) ? C2G C2G1 . 1.393(6) ? C2D C2G4 . 1.386(6) ? C2D C2E . 1.498(6) ? C2G1 C2G2 . 1.382(8) ? C2G2 C2G3 . 1.351(8) ? C2G3 C2G4 . 1.370(7) ? N3 C3A . 1.493(5) ? C3A C3' . 1.522(6) ? C3A C3B . 1.523(6) ? C3' O3 . 1.239(5) ? C3' N4 . 1.339(5) ? C3B C3G . 1.514(6) ? C3G C3D2 . 1.382(6) ? C3G C3D1 . 1.409(6) ? C3D1 C3E1 . 1.372(6) ? C3E1 C3Z . 1.384(6) ? C3Z O3Z . 1.369(5) ? C3Z C3E2 . 1.390(5) ? C3E2 C3D2 . 1.381(5) ? N4 C4A . 1.465(5) ? N4 C4E . 1.470(5) ? C4A C4B . 1.521(6) ? C4A C4' . 1.528(6) ? C4' O4' . 1.258(5) ? C4' O4 . 1.260(5) ? C4B C4G . 1.506(6) ? C4G C4G1 . 1.392(6) ? C4G C4D . 1.405(6) ? C4D C4G4 . 1.384(6) ? C4D C4E . 1.508(6) ? C4G1 C4G2 . 1.376(7) ? C4G2 C4G3 . 1.399(7) ? C4G3 C4G4 . 1.381(6) ? loop_ _geom_torsion_atom_site_label_1 _geom_torsion_atom_site_label_2 _geom_torsion_atom_site_label_3 _geom_torsion_atom_site_label_4 _geom_torsion _geom_torsion_publ_flag N1 C1A C1' N2 131.8(4) y C1A C1' N2 C2A 177.1(4) y C1' N2 C2A C2' 115.4(4) y N3 C3A C3' N4 134.6(4) y C3A C3' N4 C4A -179.0(4) y C3' N4 C4A C4' 127.1(2) y N1 C1A C1B C1G -172.5(4) y C1A C1B C1G C1D1 92.4(5) y N3 C3A C3B C3G -178.2(3) y C3A C3B C3G C3D1 86.2(5) y C1' N2 C2E C2D 131.7(4) y C1' N2 C2A C2B -118.0(4) y N2 C2A C2B C2G -46.5(5) y C2A C2B C2G C2G1 -163.3(4) y C2B C2G C2G1 C2G2 -173.6(5) y C3' N4 C4E C4D 130.0(4) y C3' N4 C4A C4B -106.1(4) y N4 C4A C4B C4G -54.6(4) y C4A C4B C4G C4G1 -158.2(4) y C4B C4G C4G1 C4G2 -179.4(4) y loop_ _cod_related_entry_id _cod_related_entry_database _cod_related_entry_code 1 ChemSpider 30652182 2 PubChem 139055696