#------------------------------------------------------------------------------ #$Date: 2025-08-19 07:12:48 +0100 (Tue, 19 Aug 2025) $ #$Revision: 301798 $ #$URL: svn://www.crystallography.net/cod/cif/2/01/15/2011528.cif $ #------------------------------------------------------------------------------ # # This file is available in the Crystallography Open Database (COD), # http://www.crystallography.net/. The original data for this entry # were provided by IUCr Journals, http://journals.iucr.org/. # # The file may be used within the scientific community so long as # proper attribution is given to the journal article from which the # data were obtained. # data_2011528 loop_ _publ_author_name 'Kansikas, Jarno' 'Sipil\"a, Kaija' _publ_section_title ;(1S,2R,2'S)- and (1S,2S,2'S)-1-phenyl-2-phenylthio-2-(tetrahydropyran-2'-ylthio)ethanol diastereoisomers at 193K ; _journal_issue 11 _journal_name_full 'Acta Crystallographica Section C' _journal_page_first 1383 _journal_page_last 1385 _journal_paper_doi 10.1107/S0108270100011161 _journal_volume 56 _journal_year 2000 _chemical_formula_sum 'C19 H22 O2 S2' _chemical_formula_weight 346.49 _space_group_IT_number 19 _symmetry_cell_setting orthorhombic _symmetry_space_group_name_Hall 'P 2ac 2ab' _symmetry_space_group_name_H-M 'P 21 21 21' _audit_creation_method SHELXL-97 _cell_angle_alpha 90.00 _cell_angle_beta 90.00 _cell_angle_gamma 90.00 _cell_formula_units_Z 4 _cell_length_a 5.3170(11) _cell_length_b 16.642(3) _cell_length_c 19.998(4) _cell_measurement_reflns_used 25 _cell_measurement_temperature 193(2) _cell_measurement_theta_max 10 _cell_measurement_theta_min 4 _cell_volume 1769.5(6) _computing_cell_refinement 'AFC7S Software' _computing_data_collection 'AFC7S Software (Molecular Structure Corporation, 1996)' _computing_data_reduction 'TEXSAN (Molecular Structure Corporation, 1993)' _computing_molecular_graphics 'SHELXTL (Bruker, 1997)' _computing_publication_material SHELXL97 _computing_structure_refinement 'SHELXL97 (Sheldrick, 1997)' _computing_structure_solution 'SHELXS97 (Sheldrick, 1990)' _diffrn_ambient_temperature 193(2) _diffrn_measured_fraction_theta_full .960 _diffrn_measured_fraction_theta_max .960 _diffrn_measurement_device_type 'Rigaku AFC7S' _diffrn_measurement_method \w/2\q _diffrn_radiation_monochromator graphite _diffrn_radiation_source 'fine-focus sealed tube' _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength .71073 _diffrn_reflns_av_R_equivalents .0000 _diffrn_reflns_av_sigmaI/netI .0326 _diffrn_reflns_limit_h_max 6 _diffrn_reflns_limit_h_min 0 _diffrn_reflns_limit_k_max 20 _diffrn_reflns_limit_k_min 0 _diffrn_reflns_limit_l_max 24 _diffrn_reflns_limit_l_min 0 _diffrn_reflns_number 2057 _diffrn_reflns_theta_full 26.45 _diffrn_reflns_theta_max 26.45 _diffrn_reflns_theta_min 2.65 _diffrn_standards_decay_% none _diffrn_standards_interval_count 100 _diffrn_standards_number 3 _exptl_absorpt_coefficient_mu .308 _exptl_absorpt_correction_type none _exptl_crystal_colour Colourless _exptl_crystal_density_diffrn 1.301 _exptl_crystal_density_method 'not measured' _exptl_crystal_description Prismatic _exptl_crystal_F_000 736 _exptl_crystal_size_max .31 _exptl_crystal_size_mid .22 _exptl_crystal_size_min .16 _refine_diff_density_max .287 _refine_diff_density_min -.216 _refine_ls_abs_structure_details 'Flack (1983)' _refine_ls_abs_structure_Flack .22(13) _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.030 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 208 _refine_ls_number_reflns 2057 _refine_ls_number_restraints 0 _refine_ls_restrained_S_all 1.030 _refine_ls_R_factor_all .0470 _refine_ls_R_factor_gt .0405 _refine_ls_shift/su_max <0.001 _refine_ls_shift/su_mean .000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_scheme ; calc w = 1/[\s^2^(Fo^2^)+(0.0549P)^2^+0.7649P] where P=(Fo^2^+2Fc^2^)/3' ; _refine_ls_wR_factor_ref .1050 _reflns_number_gt 1850 _reflns_number_total 2057 _reflns_threshold_expression I>2\s(I) _cod_data_source_file os1121.cif _cod_data_source_block I _cod_depositor_comments ; The following automatic conversions were performed: '_symmetry_cell_setting' value 'Orthorhombic' changed to 'orthorhombic' according to '/home/saulius/struct/CIF-dictionaries/cif_core.dic' dictionary named 'cif_core.dic' version 2.4.1 from 2010-06-29. Automatic conversion script Id: cif_fix_enum 1527 2010-12-29 10:47:43Z saulius The following automatic conversions were performed: '_symmetry_cell_setting' value 'Orthorhombic' changed to 'orthorhombic' according to /home/saulius/struct/CIF-dictionaries/cif_core.dic dictionary named 'cif_core.dic' version 2.4.1 from 2010-06-29. Automatic conversion script Id: cif_fix_values 1715 2011-07-08 13:25:40Z adriana ; _cod_original_sg_symbol_H-M P2~1~2~1~2~1~ _cod_database_code 2011528 _cod_database_fobs_code 2011528 loop_ _symmetry_equiv_pos_as_xyz 'x, y, z' '-x+1/2, -y, z+1/2' '-x, y+1/2, -z+1/2' 'x+1/2, -y+1/2, -z' loop_ _atom_site_label _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_calc_flag _atom_site_refinement_flags _atom_site_occupancy _atom_site_disorder_assembly _atom_site_disorder_group _atom_site_type_symbol S1 1.26462(17) .47735(5) .00516(4) .0363(2) Uani d . 1 . . S S2 .88768(19) .60495(5) .04884(4) .0384(2) Uani d . 1 . . S O1 .7835(7) .48305(15) .15859(12) .0597(9) Uani d . 1 . . O H1A .8064 .5303 .1721 .090 Uiso calc R 1 . . H O2 1.0779(6) .63379(14) .16727(12) .0482(7) Uani d . 1 . . O C1 .9723(6) .49922(18) .04820(15) .0304(7) Uani d . 1 . . C H1B .8363 .4705 .0232 .036 Uiso calc R 1 . . H C2 .9880(8) .45946(19) .11838(15) .0366(8) Uani d . 1 . . C H2A 1.1479 .4766 .1405 .044 Uiso calc R 1 . . H C3 1.1852(6) .50034(18) -.07910(14) .0308(7) Uani d . 1 . . C C4 1.3445(8) .5496(2) -.11490(17) .0402(8) Uani d . 1 . . C H4A 1.4859 .5735 -.0938 .048 Uiso calc R 1 . . H C5 1.2957(9) .5638(2) -.18224(19) .0496(10) Uani d . 1 . . C H5A 1.4079 .5962 -.2076 .060 Uiso calc R 1 . . H C6 1.0872(8) .5315(2) -.21240(16) .0439(9) Uani d . 1 . . C H6A 1.0522 .5428 -.2580 .053 Uiso calc R 1 . . H C7 .9292(8) .4827(2) -.17626(17) .0437(9) Uani d . 1 . . C H7A .7846 .4603 -.1970 .052 Uiso calc R 1 . . H C8 .9795(7) .4658(2) -.10961(16) .0392(8) Uani d . 1 . . C H8A .8728 .4307 -.0852 .047 Uiso calc R 1 . . H C9 .9842(7) .36797(19) .11338(16) .0351(8) Uani d . 1 . . C C10 .7932(8) .3282(2) .0798(2) .0482(10) Uani d . 1 . . C H10A .6619 .3578 .0591 .058 Uiso calc R 1 . . H C11 .7943(9) .2447(2) .0765(2) .0530(10) Uani d . 1 . . C H11A .6658 .2176 .0524 .064 Uiso calc R 1 . . H C12 .9786(8) .2013(2) .1076(2) .0481(10) Uani d . 1 . . C H12A .9745 .1442 .1063 .058 Uiso calc R 1 . . H C13 1.1693(9) .2400(2) .1406(2) .0536(11) Uani d . 1 . . C H13A 1.2992 .2098 .1615 .064 Uiso calc R 1 . . H C14 1.1722(8) .3240(2) .14358(17) .0427(9) Uani d . 1 . . C H14A 1.3043 .3509 .1665 .051 Uiso calc R 1 . . H C15 1.1346(8) .6476(2) .09864(17) .0384(8) Uani d . 1 . . C H15A 1.2974 .6208 .0873 .046 Uiso calc R 1 . . H C16 1.1559(9) .7374(2) .08451(18) .0495(10) Uani d . 1 . . C H16A 1.2022 .7460 .0371 .059 Uiso calc R 1 . . H H16B .9918 .7638 .0927 .059 Uiso calc R 1 . . H C17 1.3556(10) .7739(2) .1299(2) .0594(11) Uani d . 1 . . C H17A 1.5233 .7537 .1166 .071 Uiso calc R 1 . . H H17B 1.3556 .8331 .1245 .071 Uiso calc R 1 . . H C18 1.3075(11) .7532(2) .2021(2) .0634(13) Uani d . 1 . . C H18A 1.1539 .7810 .2178 .076 Uiso calc R 1 . . H H18B 1.4505 .7715 .2299 .076 Uiso calc R 1 . . H C19 1.2748(12) .6630(2) .2097(2) .0631(14) Uani d . 1 . . C H19A 1.4344 .6357 .1982 .076 Uiso calc R 1 . . H H19B 1.2344 .6503 .2568 .076 Uiso calc R 1 . . H loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_12 _atom_site_aniso_U_13 _atom_site_aniso_U_23 S1 .0327(4) .0421(4) .0340(4) .0067(4) .0005(4) .0015(4) S2 .0409(5) .0312(4) .0431(4) .0064(4) -.0027(4) .0017(3) O1 .089(2) .0382(13) .0519(14) .0061(18) .0324(17) .0001(12) O2 .072(2) .0333(12) .0394(12) -.0010(15) .0013(15) -.0010(10) C1 .0284(16) .0301(15) .0327(15) .0046(14) .0016(14) -.0008(13) C2 .050(2) .0276(16) .0323(15) .0022(17) .0043(17) .0010(13) C3 .0342(18) .0276(14) .0306(14) .0073(14) .0028(13) -.0019(12) C4 .039(2) .0384(18) .0428(17) -.0074(17) .0002(17) -.0015(15) C5 .059(3) .043(2) .0464(18) -.006(2) .010(2) .0096(16) C6 .054(2) .0451(19) .0325(15) .004(2) -.0005(18) .0005(15) C7 .045(2) .048(2) .0381(16) -.003(2) -.0038(17) -.0099(16) C8 .040(2) .0385(18) .0396(17) -.0101(17) .0044(17) -.0017(14) C9 .043(2) .0299(16) .0326(15) -.0017(16) .0030(16) .0008(13) C10 .039(2) .0381(19) .067(2) .0046(19) -.008(2) .0081(17) C11 .045(2) .043(2) .072(2) -.008(2) -.007(2) -.0025(18) C12 .052(2) .0294(17) .063(2) .0003(18) .002(2) -.0012(17) C13 .062(3) .0367(19) .062(2) .007(2) -.008(2) .0010(18) C14 .052(3) .0338(17) .0424(17) -.0026(18) -.0079(19) -.0009(14) C15 .041(2) .0314(16) .0426(17) .0022(17) .0024(18) .0012(14) C16 .061(3) .0361(18) .051(2) -.006(2) -.004(2) .0064(16) C17 .057(3) .039(2) .082(3) -.001(2) -.014(3) -.002(2) C18 .082(4) .040(2) .069(3) -.001(2) -.021(3) -.0125(19) C19 .097(4) .039(2) .053(2) .010(3) -.022(3) -.0084(17) loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C .0033 .0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H .0000 .0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O .0106 .0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' S S .1246 .1234 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_publ_flag C3 S1 C1 101.71(15) yes C15 S2 C1 101.86(16) yes C15 O2 C19 111.2(3) yes C2 C1 S1 107.3(2) yes C2 C1 S2 114.8(2) yes S1 C1 S2 114.20(17) yes O1 C2 C9 107.8(3) ? O1 C2 C1 110.8(3) yes C9 C2 C1 111.4(3) ? C8 C3 C4 120.4(3) ? C8 C3 S1 121.2(3) ? C4 C3 S1 118.3(3) ? C3 C4 C5 119.3(4) ? C6 C5 C4 120.6(4) ? C5 C6 C7 119.6(3) ? C6 C7 C8 120.5(4) ? C3 C8 C7 119.6(3) ? C14 C9 C10 119.4(3) ? C14 C9 C2 119.4(3) ? C10 C9 C2 121.2(3) ? C9 C10 C11 119.8(4) ? C12 C11 C10 120.6(4) ? C11 C12 C13 120.1(4) ? C12 C13 C14 119.9(4) ? C9 C14 C13 120.2(4) ? O2 C15 C16 110.6(3) ? O2 C15 S2 108.4(3) yes C16 C15 S2 109.8(3) ? C17 C16 C15 109.4(3) ? C18 C17 C16 111.2(4) ? C17 C18 C19 110.0(3) ? O2 C19 C18 111.1(4) ? loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_site_symmetry_2 _geom_bond_distance _geom_bond_publ_flag S1 C3 . 1.779(3) yes S1 C1 . 1.814(3) yes S2 C15 . 1.794(4) yes S2 C1 . 1.816(3) yes O1 C2 . 1.408(5) yes O2 C15 . 1.424(4) yes O2 C19 . 1.433(5) yes C1 C2 . 1.554(4) yes C2 C9 . 1.526(4) ? C3 C8 . 1.378(5) ? C3 C4 . 1.379(5) ? C4 C5 . 1.392(5) ? C5 C6 . 1.372(6) ? C6 C7 . 1.374(5) ? C7 C8 . 1.388(5) ? C9 C14 . 1.378(5) ? C9 C10 . 1.386(5) ? C10 C11 . 1.391(5) ? C11 C12 . 1.367(6) ? C12 C13 . 1.371(6) ? C13 C14 . 1.400(5) ? C15 C16 . 1.525(5) ? C16 C17 . 1.523(6) ? C17 C18 . 1.508(6) ? C18 C19 . 1.518(5) ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA O1 H1A O2 .84 2.25 2.962(4) 142.7 loop_ _geom_torsion_atom_site_label_1 _geom_torsion_atom_site_label_2 _geom_torsion_atom_site_label_3 _geom_torsion_atom_site_label_4 _geom_torsion _geom_torsion_publ_flag C3 S1 C1 C2 164.2(2) yes C3 S1 C1 S2 -67.4(2) yes C15 S2 C1 C2 58.9(3) yes C15 S2 C1 S1 -65.6(2) yes S1 C1 C2 O1 171.7(2) yes S2 C1 C2 O1 43.6(4) yes S1 C1 C2 C9 -68.3(3) yes S2 C1 C2 C9 163.6(3) yes C1 S1 C3 C8 -54.0(3) ? C1 S1 C3 C4 130.3(3) ? C8 C3 C4 C5 -.2(5) ? S1 C3 C4 C5 175.5(3) ? C3 C4 C5 C6 2.1(6) ? C4 C5 C6 C7 -2.0(6) ? C5 C6 C7 C8 -.1(6) ? C4 C3 C8 C7 -1.8(5) ? S1 C3 C8 C7 -177.4(3) ? C6 C7 C8 C3 2.0(6) ? O1 C2 C9 C14 -111.8(4) ? C1 C2 C9 C14 126.4(4) ? O1 C2 C9 C10 67.3(4) ? C1 C2 C9 C10 -54.5(5) ? C14 C9 C10 C11 -.5(6) ? C2 C9 C10 C11 -179.6(4) ? C9 C10 C11 C12 1.7(7) ? C10 C11 C12 C13 -2.1(6) ? C11 C12 C13 C14 1.3(6) ? C10 C9 C14 C13 -.4(6) ? C2 C9 C14 C13 178.8(3) ? C12 C13 C14 C9 .0(6) ? C19 O2 C15 C16 -62.4(4) ? C19 O2 C15 S2 177.2(2) ? C1 S2 C15 O2 -80.0(3) yes C1 S2 C15 C16 159.1(3) yes O2 C15 C16 C17 57.1(5) ? S2 C15 C16 C17 176.8(3) ? C15 C16 C17 C18 -52.5(5) ? C16 C17 C18 C19 52.1(6) ? C15 O2 C19 C18 61.9(5) ? C17 C18 C19 O2 -56.1(6) ? loop_ _cod_related_entry_id _cod_related_entry_database _cod_related_entry_code 1 ChemSpider 21182302 2 PubChem 101079308