#------------------------------------------------------------------------------ #$Date: 2013-12-28 13:58:47 +0000 (Sat, 28 Dec 2013) $ #$Revision: 91933 $ #$URL: svn://www.crystallography.net/cod/cif/2/01/20/2012017.cif $ #------------------------------------------------------------------------------ # # This file is available in the Crystallography Open Database (COD), # http://www.crystallography.net/. The original data for this entry # were provided by IUCr Journals, http://journals.iucr.org/. # # The file may be used within the scientific community so long as # proper attribution is given to the journal article from which the # data were obtained. # data_2012017 loop_ _publ_author_name 'Mark, Brian L.' 'Parrish, Jonathan C.' 'Wang, Zhi-Xian' 'Wiebe, Leonard I.' 'Knaus, Edward E.' 'James, Michael N. G.' _publ_section_title (E)-1-(2'-Deoxy-\b-D-ribofuranosyl)-2,4-difluoro-5-(2-iodovinyl)benzene _journal_issue 6 _journal_name_full 'Acta Crystallographica Section C' _journal_page_first 758 _journal_page_last 760 _journal_volume 57 _journal_year 2001 _chemical_formula_moiety 'C13 H13 F2 I O3' _chemical_formula_sum 'C13 H13 F2 I O3' _chemical_formula_weight 382.13 _chemical_melting_point 359.0(10) _chemical_name_systematic ; 2,4-Difluoro-(E)-5-(2-iodovinyl)-1-(2'-deoxy-\b-D-ribofuranosyl)benzene ; _space_group_IT_number 4 _symmetry_cell_setting monoclinic _symmetry_space_group_name_Hall 'P 2yb' _symmetry_space_group_name_H-M 'P 1 21 1' _audit_creation_method SHELXL-97 _cell_angle_alpha 90.00 _cell_angle_beta 96.5141(14) _cell_angle_gamma 90.00 _cell_formula_units_Z 2 _cell_length_a 9.2884(8) _cell_length_b 6.7527(6) _cell_length_c 10.6582(9) _cell_measurement_reflns_used 4139 _cell_measurement_temperature 193(2) _cell_measurement_theta_max 25.68 _cell_measurement_theta_min 1.92 _cell_volume 664.19(10) _computing_cell_refinement 'SMART (Siemens, 1996)' _computing_data_collection 'SMART (Siemens, 1996)' _computing_data_reduction 'SHELXTL (Sheldrick, 1996)' _computing_molecular_graphics 'ZORTEP (Zsolnai & Huttner, 1994)' _computing_structure_refinement 'SHELXL97 (Sheldrick, 1997b)' _computing_structure_solution 'DIRDIF-99 (Beurskens et al., 1998)' _diffrn_ambient_temperature 193(2) _diffrn_measured_fraction_theta_full .998 _diffrn_measured_fraction_theta_max .998 _diffrn_measurement_device 'Bruker SMART CCD' _diffrn_measurement_method '\f and \w scans' _diffrn_radiation_monochromator graphite _diffrn_radiation_source 'fine-focus sealed tube' _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength .71073 _diffrn_reflns_av_R_equivalents .0250 _diffrn_reflns_av_sigmaI/netI .0374 _diffrn_reflns_limit_h_max 11 _diffrn_reflns_limit_h_min -11 _diffrn_reflns_limit_k_max 8 _diffrn_reflns_limit_k_min -8 _diffrn_reflns_limit_l_max 12 _diffrn_reflns_limit_l_min -12 _diffrn_reflns_number 4141 _diffrn_reflns_theta_full 25.68 _diffrn_reflns_theta_max 25.68 _diffrn_reflns_theta_min 1.92 _diffrn_standards_decay_% 0 _diffrn_standards_number 0 _exptl_absorpt_coefficient_mu 2.435 _exptl_absorpt_correction_T_max .862 _exptl_absorpt_correction_T_min .560 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details '(SADABS; Sheldrick, 1997a)' _exptl_crystal_colour 'clear pale yellow' _exptl_crystal_density_diffrn 1.911 _exptl_crystal_density_method 'not measured' _exptl_crystal_description plate _exptl_crystal_F_000 372 _exptl_crystal_size_max .23 _exptl_crystal_size_mid .18 _exptl_crystal_size_min .04 _refine_diff_density_max .970 _refine_diff_density_min -.307 _refine_ls_abs_structure_details 'Flack (1983)' _refine_ls_abs_structure_Flack -.04(3) _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.021 _refine_ls_hydrogen_treatment mixed _refine_ls_matrix_type full _refine_ls_number_parameters 174 _refine_ls_number_reflns 2464 _refine_ls_number_restraints 1 _refine_ls_restrained_S_all 1.020 _refine_ls_R_factor_all .0394 _refine_ls_R_factor_gt .0372 _refine_ls_shift/su_max .000 _refine_ls_shift/su_mean .000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'calc w=1/[\s^2^(Fo^2^)+(0.0690P)^2^] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_ref .0953 _reflns_number_gt 2334 _reflns_number_total 2464 _reflns_threshold_expression I>2\s(I) _[local]_cod_data_source_file da1180.cif _[local]_cod_data_source_block I _[local]_cod_cif_authors_sg_H-M 'P 21' _cod_depositor_comments ; The following automatic conversions were performed: '_symmetry_cell_setting' value 'Monoclinic' changed to 'monoclinic' according to '/home/saulius/struct/CIF-dictionaries/cif_core.dic' dictionary named 'cif_core.dic' version 2.4.1 from 2010-06-29. Automatic conversion script Id: cif_fix_enum 1527 2010-12-29 10:47:43Z saulius The following automatic conversions were performed: '_chemical_melting_point' value '358-360' was changed to '359.0(10)' - the average value was taken and precision was estimated. Automatic conversion script Id: cif_fix_values 1646 2011-03-28 12:23:43Z adriana The following automatic conversions were performed: '_chemical_melting_point' value '358-360' was changed to '359.0(10)' - the average value was taken and precision was estimated. '_symmetry_cell_setting' value 'Monoclinic' changed to 'monoclinic' according to /home/saulius/struct/CIF-dictionaries/cif_core.dic dictionary named 'cif_core.dic' version 2.4.1 from 2010-06-29. Automatic conversion script Id: cif_fix_values 1715 2011-07-08 13:25:40Z adriana ; _cod_database_code 2012017 loop_ _symmetry_equiv_pos_as_xyz 'x, y, z' '-x, y+1/2, -z' loop_ _atom_site_label _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_calc_flag _atom_site_refinement_flags _atom_site_occupancy _atom_site_disorder_assembly _atom_site_disorder_group _atom_site_type_symbol C1' -.3620(6) -.6186(7) .1474(5) .0250(10) Uani d . 1 . . C H1' -.4137 -.7481 .1507 .030 Uiso calc R 1 . . H O4' -.4659(4) -.4616(5) .1352(3) .0284(9) Uani d . 1 . . O C2' -.2724(6) -.5816(9) .2732(5) .0322(12) Uani d . 1 . . C H2A' -.1966 -.4809 .2653 .039 Uiso calc R 1 . . H H2B' -.2263 -.7051 .3080 .039 Uiso calc R 1 . . H C3' -.3851(5) -.5068(11) .3548(4) .0281(9) Uani d . 1 . . C H3A' -.3400 -.4252 .4271 .034 Uiso calc R 1 . . H O3' -.4620(5) -.6716(6) .3970(4) .0404(10) Uani d . 1 . . O H3' -.4770 -.6536 .4724 .061 Uiso calc R 1 . . H C4' -.4816(6) -.3807(7) .2590(5) .0252(10) Uani d . 1 . . C H4' -.5848 -.3947 .2759 .030 Uiso calc R 1 . . H C5' -.4428(6) -.1640(8) .2587(5) .0298(11) Uani d . 1 . . C H5A' -.3362 -.1479 .2686 .036 Uiso calc R 1 . . H H5B' -.4824 -.1027 .1776 .036 Uiso calc R 1 . . H O5' -.5023(5) -.0713(6) .3601(4) .0340(10) Uani d . 1 . . O H5' -.4628 .0396 .3745 .051 Uiso calc R 1 . . H C1 -.2751(6) -.6183(8) .0351(5) .0265(10) Uani d . 1 . . C C2 -.1946(7) -.7827(8) .0110(6) .0331(12) Uani d . 1 . . C F2 -.2025(4) -.9461(5) .0850(4) .0481(10) Uani d . 1 . . F C3 -.1057(7) -.7922(9) -.0835(6) .0362(13) Uani d . 1 . . C H3 -.0492 -.9064 -.0956 .043 Uiso calc R 1 . . H C4 -.1027(6) -.6278(9) -.1597(5) .0328(12) Uani d . 1 . . C F4 -.0133(4) -.6362(5) -.2516(3) .0431(8) Uani d . 1 . . F C5 -.1823(6) -.4566(8) -.1446(5) .0297(12) Uani d . 1 . . C C7 -.1875(6) -.2832(9) -.2286(5) .0339(12) Uani d . 1 . . C H7 -.2428 -.1738 -.2050 .041 Uiso calc R 1 . . H C8 -.1247(7) -.2612(9) -.3326(6) .0372(13) Uani d . 1 . . C H8 -.0659 -.3662 -.3572 .045 Uiso calc R 1 . . H I8 -.14684(4) -.01161(7) -.44498(3) .04307(15) Uani d . 1 . . I C6 -.2672(6) -.4565(7) -.0432(5) .0273(11) Uani d . 1 . . C H6 -.3210 -.3410 -.0281 .033 Uiso calc R 1 . . H loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_12 _atom_site_aniso_U_13 _atom_site_aniso_U_23 C1' .032(3) .017(2) .027(3) .003(2) .007(2) .0013(19) O4' .0348(19) .029(2) .0219(17) .0066(14) .0033(14) -.0036(13) C2' .033(3) .040(3) .025(3) .007(2) .006(2) .007(2) C3' .042(2) .021(2) .0221(19) .000(3) .0081(17) .008(3) O3' .073(3) .0210(19) .032(2) -.0044(19) .026(2) -.0015(16) C4' .027(3) .025(3) .024(3) .001(2) .008(2) -.005(2) C5' .041(3) .023(2) .024(3) .001(2) .002(2) .002(2) O5' .052(3) .021(2) .032(2) -.0029(15) .0147(18) -.0023(14) C1 .027(3) .027(3) .026(3) .000(2) .004(2) .002(2) C2 .041(3) .028(3) .031(3) .006(2) .005(2) .000(2) F2 .060(2) .036(2) .053(2) .0172(16) .0250(19) .0146(16) C3 .040(3) .035(3) .034(3) .008(2) .008(2) -.002(2) C4 .031(3) .042(3) .027(3) .000(2) .009(2) -.007(2) F4 .048(2) .049(2) .0359(19) .0022(16) .0210(15) -.0050(16) C5 .030(3) .034(3) .025(2) -.004(2) .004(2) -.0008(19) C7 .034(3) .036(3) .032(3) .000(2) .008(2) .004(2) C8 .044(3) .036(3) .034(3) .000(2) .013(3) .008(2) I8 .0498(2) .0495(2) .0312(2) -.0069(3) .01021(14) .0101(2) C6 .030(3) .025(3) .027(2) .0011(18) .002(2) -.0035(18) loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_site_symmetry_2 _geom_bond_distance _geom_bond_publ_flag C1 C2 . 1.379(8) yes C2 C3 . 1.373(8) yes C3 C4 . 1.378(9) yes C4 C5 . 1.391(8) yes C5 C6 . 1.409(7) yes C6 C1 . 1.382(7) yes C1 C1' . 1.518(7) yes C2 F2 . 1.363(7) yes C4 F4 . 1.355(6) yes C5 C7 . 1.471(8) yes C7 C8 . 1.318(8) yes C8 I8 . 2.064(6) yes C1' O4' . 1.429(6) no C1' C2' . 1.517(8) no C1' H1' . 1.0000 no O4' C4' . 1.450(6) no C2' C3' . 1.521(7) no C2' H2A' . .9900 no C2' H2B' . .9900 no C3' O3' . 1.423(7) no C3' C4' . 1.537(7) no C3' H3A' . 1.0000 no O3' H3' . .8400 no C4' C5' . 1.508(7) no C4' H4' . 1.0000 no C5' O5' . 1.415(7) no C5' H5A' . .9900 no C5' H5B' . .9900 no O5' H5' . .8400 no C3 H3 . .9500 no C7 H7 . .9500 no C8 H8 . .9500 no C6 H6 . .9500 no loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C .0033 .0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H .0000 .0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O .0106 .0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' F F .0171 .0103 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' I I -.4742 1.8119 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_publ_flag C1 C2 F2 118.6(5) yes C3 C2 F2 117.6(5) yes C3 C4 F4 116.6(5) yes C5 C4 F4 119.7(5) yes C4 C5 C7 124.9(5) yes C6 C5 C7 118.9(5) yes C5 C7 C8 127.9(6) yes C7 C8 I8 123.7(5) yes O4' C1' C2' 104.8(4) no O4' C1' C1 110.0(4) no C2' C1' C1 114.2(4) no O4' C1' H1' 109.3 no C2' C1' H1' 109.3 no C1 C1' H1' 109.3 no C1' O4' C4' 109.5(4) no C1' C2' C3' 102.5(4) no C1' C2' H2A' 111.3 no C3' C2' H2A' 111.3 no C1' C2' H2B' 111.3 no C3' C2' H2B' 111.3 no H2A' C2' H2B' 109.2 no O3' C3' C2' 108.9(5) no O3' C3' C4' 111.6(4) no C2' C3' C4' 101.1(4) no O3' C3' H3A' 111.6 no C2' C3' H3A' 111.6 no C4' C3' H3A' 111.6 no C3' O3' H3' 109.5 no O4' C4' C5' 108.4(4) no O4' C4' C3' 106.5(4) no C5' C4' C3' 114.7(5) no O4' C4' H4' 109.0 no C5' C4' H4' 109.0 no C3' C4' H4' 109.0 no O5' C5' C4' 108.3(4) no O5' C5' H5A' 110.0 no C4' C5' H5A' 110.0 no O5' C5' H5B' 110.0 no C4' C5' H5B' 110.0 no H5A' C5' H5B' 108.4 no C5' O5' H5' 109.5 no C2 C1 C6 117.2(5) no C2 C1 C1' 119.6(5) no C6 C1 C1' 123.1(5) no C3 C2 C1 123.9(5) no C2 C3 C4 116.7(5) no C2 C3 H3 121.7 no C4 C3 H3 121.7 no C3 C4 C5 123.6(5) no C4 C5 C6 116.1(5) no C8 C7 H7 116.1 no C5 C7 H7 116.1 no C7 C8 H8 118.1 no I8 C8 H8 118.1 no C1 C6 C5 122.4(5) no C1 C6 H6 118.8 no C5 C6 H6 118.8 no loop_ _geom_torsion_atom_site_label_1 _geom_torsion_atom_site_label_2 _geom_torsion_atom_site_label_3 _geom_torsion_atom_site_label_4 _geom_torsion _geom_torsion_publ_flag O4' C1' C2' C3' 37.3(5) yes C1' C2' C3' C4' -37.8(5) yes C2' C3' C4' O4' 25.9(6) yes C3' C4' O4' C1' -3.2(5) yes C4' O4' C1' C2' -21.3(5) yes O4' C4' C5' O5' 160.8(4) yes C3' C4' C5' O5' -80.4(5) yes C2' C1' C1 C2 78.4(6) yes O4' C1' C1 C2 -164.2(5) yes C2' C1' C1 C6 -98.9(6) yes O4' C1' C1 C6 18.5(7) yes C4 C5 C7 C8 2.8(10) yes C6 C5 C7 C8 -174.8(6) yes C5 C7 C8 I8 177.9(5) yes C2' C3' C4' C5' -93.9(5) no C1 C1' O4' C4' -144.4(4) no C1 C1' C2' C3' 157.7(5) no C1' C2' C3' O3' 79.8(5) no C1' O4' C4' C5' 120.7(4) no O3' C3' C4' O4' -89.7(5) no O3' C3' C4' C5' 150.5(4) no C6 C1 C2 F2 -178.7(5) no C1' C1 C2 F2 3.8(8) no C6 C1 C2 C3 1.6(9) no C1' C1 C2 C3 -175.9(6) no F2 C2 C3 C4 178.0(5) no C1 C2 C3 C4 -2.2(9) no C2 C3 C4 F4 179.0(5) no C2 C3 C4 C5 .8(9) no F4 C4 C5 C6 -177.1(5) no C3 C4 C5 C6 1.1(8) no F4 C4 C5 C7 5.3(8) no C3 C4 C5 C7 -176.5(6) no C2 C1 C6 C5 .5(8) no C1' C1 C6 C5 177.9(5) no C4 C5 C6 C1 -1.8(8) no C7 C5 C6 C1 176.0(5) no _journal_paper_doi 10.1107/S0108270101005029