#------------------------------------------------------------------------------ #$Date: 2015-01-23 12:30:19 +0000 (Fri, 23 Jan 2015) $ #$Revision: 130086 $ #$URL: svn://www.crystallography.net/cod/cif/2/01/29/2012964.cif $ #------------------------------------------------------------------------------ # # This file is available in the Crystallography Open Database (COD), # http://www.crystallography.net/. The original data for this entry # were provided by IUCr Journals, http://journals.iucr.org/. # # The file may be used within the scientific community so long as # proper attribution is given to the journal article from which the # data were obtained. # data_2012964 loop_ _publ_author_name 'V\'azquez, Edna' 'Galindo, Alberto' 'Bern\`es, Sylvain' 'Gnecco, Dino' _publ_section_title ;(--)-(1'S,4aS,7R,8aR)-4a-Ethyl-7-hydroxy-1-(1'-phenylethyl)perhydroquinolinium bromide ; _journal_issue 10 _journal_name_full 'Acta Crystallographica Section C' _journal_page_first o591 _journal_page_last o592 _journal_paper_doi 10.1107/S0108270102014725 _journal_volume 58 _journal_year 2002 _chemical_formula_moiety 'C19 H30 N O + , Br -' _chemical_formula_sum 'C19 H30 Br N O' _chemical_formula_weight 368.35 _chemical_melting_point 403 _chemical_name_systematic ; (-)-(1'S,4aS,7R,8aR)-4a-ethyl-1-(1'-phenylethyl)octahydroquinolinium-7-ol bromide ; _space_group_IT_number 4 _symmetry_cell_setting monoclinic _symmetry_space_group_name_Hall 'P 2yb' _symmetry_space_group_name_H-M 'P 1 21 1' _atom_sites_solution_hydrogens 'see text' _atom_sites_solution_primary direct _atom_sites_solution_secondary difmap _audit_creation_method SHELXL97 _cell_angle_alpha 90 _cell_angle_beta 92.624(7) _cell_angle_gamma 90 _cell_formula_units_Z 2 _cell_length_a 9.6977(8) _cell_length_b 9.2191(7) _cell_length_c 10.3008(8) _cell_measurement_reflns_used 61 _cell_measurement_temperature 300.0(10) _cell_measurement_theta_max 12.51 _cell_measurement_theta_min 4.53 _cell_volume 919.97(13) _computing_cell_refinement XSCANS _computing_data_collection 'XSCANS (Siemens, 1996)' _computing_data_reduction XSCANS _computing_molecular_graphics SHELXTL-Plus _computing_publication_material SHELXL97 _computing_structure_refinement 'SHELXL97 (Sheldrick, 1997)' _computing_structure_solution 'SHELXTL-Plus (Sheldrick, 1998)' _diffrn_ambient_temperature 300.0(10) _diffrn_measured_fraction_theta_full 1.000 _diffrn_measured_fraction_theta_max 1.000 _diffrn_measurement_device_type 'Bruker P4' _diffrn_measurement_method '2\q/\w scans' _diffrn_radiation_monochromator graphite _diffrn_radiation_source 'fine-focus sealed tube' _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_reflns_av_R_equivalents 0.028 _diffrn_reflns_av_sigmaI/netI 0.035 _diffrn_reflns_limit_h_max 12 _diffrn_reflns_limit_h_min -12 _diffrn_reflns_limit_k_max 12 _diffrn_reflns_limit_k_min -12 _diffrn_reflns_limit_l_max 13 _diffrn_reflns_limit_l_min -13 _diffrn_reflns_number 6148 _diffrn_reflns_theta_full 27.99 _diffrn_reflns_theta_max 27.99 _diffrn_reflns_theta_min 1.98 _diffrn_standards_decay_% 2.5 _diffrn_standards_interval_count 97 _diffrn_standards_number 3 _exptl_absorpt_coefficient_mu 2.237 _exptl_absorpt_correction_T_max 0.409 _exptl_absorpt_correction_T_min 0.292 _exptl_absorpt_correction_type '\y scan' _exptl_absorpt_process_details '(30 \y scans with XSCANS; Siemens, 1996)' _exptl_crystal_colour colourless _exptl_crystal_density_diffrn 1.330 _exptl_crystal_density_meas ? _exptl_crystal_density_method 'not measured' _exptl_crystal_description block _exptl_crystal_F_000 388 _exptl_crystal_size_max 0.62 _exptl_crystal_size_mid 0.60 _exptl_crystal_size_min 0.40 _refine_diff_density_max 0.28 _refine_diff_density_min -0.29 _refine_ls_abs_structure_details 'Flack (1983); 2088 Friedel pairs' _refine_ls_abs_structure_Flack 0.002(8) _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.019 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 199 _refine_ls_number_reflns 4443 _refine_ls_number_restraints 1 _refine_ls_restrained_S_all 1.019 _refine_ls_R_factor_all 0.044 _refine_ls_R_factor_gt 0.033 _refine_ls_shift/su_max 0.001 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'calc w = 1/[\s^2^(Fo^2^)+(0.0358P)^2^+0.1874P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.074 _refine_ls_wR_factor_ref 0.079 _reflns_number_gt 3804 _reflns_number_total 4443 _reflns_threshold_expression I>2\s(I) _[local]_cod_data_source_file bm1506.cif _[local]_cod_data_source_block I _[local]_cod_cif_authors_sg_H-M 'P 21' _cod_depositor_comments ; The following automatic conversions were performed: '_symmetry_cell_setting' value 'Monoclinic' changed to 'monoclinic' according to '/home/saulius/struct/CIF-dictionaries/cif_core.dic' dictionary named 'cif_core.dic' version 2.4.1 from 2010-06-29. Automatic conversion script Id: cif_fix_enum 1527 2010-12-29 10:47:43Z saulius The following automatic conversions were performed: '_symmetry_cell_setting' value 'Monoclinic' changed to 'monoclinic' according to /home/saulius/struct/CIF-dictionaries/cif_core.dic dictionary named 'cif_core.dic' version 2.4.1 from 2010-06-29. '_geom_hbond_publ_flag' value 'Yes' changed to 'yes' according to /home/saulius/struct/CIF-dictionaries/cif_core.dic dictionary named 'cif_core.dic' version 2.4.1 from 2010-06-29 (2 times). Automatic conversion script Id: cif_fix_values 1715 2011-07-08 13:25:40Z adriana The following automatic conversions were performed: '_exptl_crystal_density_meas' value 'not measured' was changed to '?' - the value is perceived as not measured. Automatic conversion script Id: cif_fix_values 3008 2015-01-20 13:52:24Z robertas ; _cod_database_code 2012964 _cod_database_fobs_code 2012964 loop_ _symmetry_equiv_pos_as_xyz 'x, y, z' '-x, y+1/2, -z' loop_ _atom_site_label _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_calc_flag _atom_site_refinement_flags _atom_site_occupancy _atom_site_disorder_assembly _atom_site_disorder_group _atom_site_type_symbol Br1 0.41070(2) -0.06005(3) 0.71041(3) 0.05686(9) Uani d . 1 . . Br N1 0.2932(2) 0.2967(2) 0.67736(19) 0.0362(4) Uani d . 1 . . N H1 0.3168 0.2065 0.7068 0.043 Uiso d R 1 . . H C1' 0.1942(3) 0.2839(3) 0.5576(2) 0.0404(5) Uani d . 1 . . C H1'A 0.1799 0.3817 0.5221 0.048 Uiso calc R 1 . . H C2 0.4335(3) 0.3514(3) 0.6439(3) 0.0483(6) Uani d . 1 . . C H2A 0.4246 0.4477 0.6066 0.058 Uiso calc R 1 . . H H2B 0.4716 0.2881 0.5793 0.058 Uiso calc R 1 . . H C2' 0.2535(3) 0.1907(4) 0.4514(3) 0.0548(7) Uani d . 1 . . C H2'A 0.1888 0.1863 0.3781 0.082 Uiso calc R 1 . . H H2'B 0.2705 0.0945 0.4841 0.082 Uiso calc R 1 . . H H2'C 0.3385 0.2324 0.4251 0.082 Uiso calc R 1 . . H C3 0.5308(3) 0.3566(3) 0.7630(3) 0.0522(6) Uani d . 1 . . C H3A 0.6169 0.4011 0.7397 0.063 Uiso calc R 1 . . H H3B 0.5510 0.2583 0.7915 0.063 Uiso calc R 1 . . H C4 0.4722(2) 0.4412(4) 0.8752(2) 0.0459(5) Uani d . 1 . . C H4A 0.4667 0.5431 0.8521 0.055 Uiso calc R 1 . . H H4B 0.5344 0.4321 0.9512 0.055 Uiso calc R 1 . . H C4a 0.3282(2) 0.3873(3) 0.9088(2) 0.0377(5) Uani d . 1 . . C C5 0.2667(3) 0.4886(3) 1.0097(3) 0.0457(6) Uani d . 1 . . C H5A 0.1826 0.4449 1.0389 0.055 Uiso calc R 1 . . H H5B 0.3312 0.4950 1.0842 0.055 Uiso calc R 1 . . H C6 0.2334(3) 0.6418(3) 0.9622(3) 0.0527(7) Uani d . 1 . . C H6A 0.1903 0.6961 1.0302 0.063 Uiso calc R 1 . . H H6B 0.3179 0.6914 0.9415 0.063 Uiso calc R 1 . . H C7 0.1376(3) 0.6347(3) 0.8435(3) 0.0477(6) Uani d . 1 . . C H7A 0.0519 0.5881 0.8687 0.057 Uiso calc R 1 . . H C8 0.1976(3) 0.5428(3) 0.7367(3) 0.0434(6) Uani d . 1 . . C H8A 0.2808 0.5886 0.7076 0.052 Uiso calc R 1 . . H H8B 0.1316 0.5375 0.6632 0.052 Uiso calc R 1 . . H C8a 0.2319(2) 0.3891(2) 0.7848(2) 0.0331(5) Uani d . 1 . . C H8AA 0.1448 0.3435 0.8071 0.040 Uiso calc R 1 . . H C9 0.3428(3) 0.2344(3) 0.9701(3) 0.0460(6) Uani d . 1 . . C H9A 0.3858 0.1717 0.9080 0.055 Uiso calc R 1 . . H H9B 0.4058 0.2415 1.0457 0.055 Uiso calc R 1 . . H C10 0.2122(3) 0.1606(4) 1.0115(3) 0.0635(8) Uani d . 1 . . C H10A 0.2345 0.0663 1.0461 0.095 Uiso calc R 1 . . H H10B 0.1487 0.1507 0.9377 0.095 Uiso calc R 1 . . H H10C 0.1706 0.2180 1.0769 0.095 Uiso calc R 1 . . H C11 0.0548(3) 0.2270(3) 0.5962(2) 0.0381(5) Uani d . 1 . . C C12 -0.0640(3) 0.2955(3) 0.5487(3) 0.0481(6) Uani d . 1 . . C H12A -0.0571 0.3797 0.4996 0.058 Uiso calc R 1 . . H C12' 0.0431(3) 0.1028(3) 0.6703(2) 0.0405(5) Uani d . 1 . . C H12B 0.1222 0.0552 0.7022 0.049 Uiso calc R 1 . . H C13 -0.1929(3) 0.2402(4) 0.5732(3) 0.0532(7) Uani d . 1 . . C H13A -0.2720 0.2861 0.5394 0.064 Uiso calc R 1 . . H C13' -0.0859(3) 0.0487(3) 0.6974(3) 0.0459(6) Uani d . 1 . . C H13B -0.0929 -0.0336 0.7489 0.055 Uiso calc R 1 . . H C14 -0.2040(3) 0.1165(3) 0.6482(3) 0.0487(6) Uani d . 1 . . C H14A -0.2904 0.0793 0.6653 0.058 Uiso calc R 1 . . H O15 0.1029(2) 0.7752(2) 0.7937(2) 0.0677(6) Uani d . 1 . . O H15 0.1687 0.8096 0.7759 0.102 Uiso d R 1 . . H loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_12 _atom_site_aniso_U_13 _atom_site_aniso_U_23 Br1 0.05259(13) 0.04875(13) 0.06874(17) -0.00308(17) -0.00264(10) 0.00670(17) N1 0.0352(9) 0.0334(9) 0.0404(10) -0.0005(8) 0.0055(8) -0.0021(8) C1' 0.0470(13) 0.0404(12) 0.0338(11) -0.0018(11) 0.0009(10) 0.0027(10) C2 0.0410(13) 0.0516(15) 0.0538(15) -0.0054(11) 0.0173(11) -0.0055(12) C2' 0.0604(18) 0.0638(18) 0.0409(14) -0.0062(15) 0.0103(13) -0.0106(13) C3 0.0350(12) 0.0540(15) 0.0682(17) -0.0020(12) 0.0072(12) -0.0117(14) C4 0.0394(10) 0.0423(10) 0.0556(12) -0.0057(17) -0.0005(9) -0.0038(18) C4a 0.0374(11) 0.0344(10) 0.0413(12) 0.0031(9) 0.0015(9) -0.0022(9) C5 0.0524(14) 0.0443(13) 0.0405(13) 0.0078(10) 0.0019(11) -0.0055(10) C6 0.0609(18) 0.0414(14) 0.0561(16) 0.0115(13) 0.0072(13) -0.0101(12) C7 0.0505(14) 0.0346(12) 0.0584(16) 0.0131(11) 0.0054(13) 0.0022(11) C8 0.0474(14) 0.0362(12) 0.0465(14) 0.0078(11) -0.0002(11) 0.0030(11) C8a 0.0337(11) 0.0306(10) 0.0355(11) 0.0022(8) 0.0063(9) -0.0006(8) C9 0.0520(15) 0.0411(13) 0.0448(14) 0.0070(11) -0.0004(11) 0.0054(11) C10 0.0680(19) 0.0523(16) 0.070(2) -0.0029(15) 0.0039(16) 0.0171(15) C11 0.0435(12) 0.0361(11) 0.0345(11) -0.0009(10) -0.0005(9) -0.0002(9) C12 0.0537(15) 0.0461(14) 0.0445(14) 0.0085(12) 0.0006(11) 0.0107(11) C12' 0.0426(12) 0.0360(11) 0.0426(13) 0.0027(10) -0.0017(10) 0.0003(10) C13 0.0452(15) 0.0674(19) 0.0468(15) 0.0132(13) -0.0003(12) 0.0020(14) C13' 0.0499(14) 0.0407(12) 0.0477(14) -0.0013(11) 0.0095(11) -0.0013(11) C14 0.0417(13) 0.0555(15) 0.0494(15) -0.0003(12) 0.0063(11) -0.0116(12) O15 0.0782(15) 0.0380(10) 0.0868(16) 0.0238(10) 0.0010(13) 0.0044(10) loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' N N 0.0061 0.0033 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' Br Br -0.2901 2.4595 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' loop_ _diffrn_standard_refln_index_h _diffrn_standard_refln_index_k _diffrn_standard_refln_index_l 5 -2 2 2 0 -6 0 -2 1 loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_publ_flag C2 N1 C1' 112.36(18) n C2 N1 C8a 111.25(18) n C1' N1 C8a 111.93(17) n C11 C1' C2' 111.3(2) n C11 C1' N1 110.33(18) n C2' C1' N1 112.2(2) n N1 C2 C3 111.2(2) n C2 C3 C4 113.0(2) n C3 C4 C4a 112.3(2) n C4 C4a C5 109.9(2) y C4 C4a C8a 109.32(19) y C5 C4a C8a 108.21(19) y C4 C4a C9 108.6(2) y C5 C4a C9 108.0(2) y C8a C4a C9 112.7(2) y C6 C5 C4a 115.4(2) n C7 C6 C5 109.5(2) n O15 C7 C6 112.3(2) y O15 C7 C8 109.6(2) y C6 C7 C8 111.7(2) y C7 C8 C8a 111.4(2) n C8 C8a N1 111.40(19) n C8 C8a C4a 113.00(19) n N1 C8a C4a 110.45(17) n C10 C9 C4a 117.5(2) n C12 C11 C12' 119.0(2) n C12 C11 C1' 119.1(2) n C12' C11 C1' 121.8(2) n C11 C12 C13 120.8(2) n C11 C12' C13' 120.4(2) n C14 C13 C12 119.9(3) n C14 C13' C12' 120.3(3) n C13' C14 C13 119.6(3) n C2 N1 H1 99.6 ? C1' N1 H1 109.7 ? C8a N1 H1 111.4 ? C11 C1' H1'A 107.6 ? C2' C1' H1'A 107.6 ? N1 C1' H1'A 107.6 ? N1 C2 H2A 109.4 ? C3 C2 H2A 109.4 ? N1 C2 H2B 109.4 ? C3 C2 H2B 109.4 ? H2A C2 H2B 108.0 ? C1' C2' H2'A 109.5 ? C1' C2' H2'B 109.5 ? H2'A C2' H2'B 109.5 ? C1' C2' H2'C 109.5 ? H2'A C2' H2'C 109.5 ? H2'B C2' H2'C 109.5 ? C2 C3 H3A 109.0 ? C4 C3 H3A 109.0 ? C2 C3 H3B 109.0 ? C4 C3 H3B 109.0 ? H3A C3 H3B 107.8 ? C3 C4 H4A 109.1 ? C4a C4 H4A 109.1 ? C3 C4 H4B 109.1 ? C4a C4 H4B 109.1 ? H4A C4 H4B 107.9 ? C6 C5 H5A 108.4 ? C4a C5 H5A 108.4 ? C6 C5 H5B 108.4 ? C4a C5 H5B 108.4 ? H5A C5 H5B 107.5 ? C7 C6 H6A 109.8 ? C5 C6 H6A 109.8 ? C7 C6 H6B 109.8 ? C5 C6 H6B 109.8 ? H6A C6 H6B 108.2 ? O15 C7 H7A 107.7 ? C6 C7 H7A 107.7 ? C8 C7 H7A 107.7 ? C7 C8 H8A 109.4 ? C8a C8 H8A 109.4 ? C7 C8 H8B 109.4 ? C8a C8 H8B 109.4 ? H8A C8 H8B 108.0 ? C8 C8a H8AA 107.2 ? N1 C8a H8AA 107.2 ? C4a C8a H8AA 107.2 ? C10 C9 H9A 107.9 ? C4a C9 H9A 107.9 ? C10 C9 H9B 107.9 ? C4a C9 H9B 107.9 ? H9A C9 H9B 107.2 ? C9 C10 H10A 109.5 ? C9 C10 H10B 109.5 ? H10A C10 H10B 109.5 ? C9 C10 H10C 109.5 ? H10A C10 H10C 109.5 ? H10B C10 H10C 109.5 ? C11 C12 H12A 119.6 ? C13 C12 H12A 119.6 ? C11 C12' H12B 119.8 ? C13' C12' H12B 119.8 ? C12 C13 H13A 120.0 ? C14 C13 H13A 120.0 ? C14 C13' H13B 119.9 ? C12' C13' H13B 119.9 ? C13' C14 H14A 120.2 ? C13 C14 H14A 120.2 ? C7 O15 H15 106.6 ? loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_site_symmetry_2 _geom_bond_distance _geom_bond_publ_flag N1 C2 . 1.506(3) n N1 C1' . 1.533(3) n N1 C8a . 1.538(3) y C1' C11 . 1.520(3) n C1' C2' . 1.524(4) n C2 C3 . 1.514(4) n C3 C4 . 1.525(4) n C4 C4a . 1.536(3) n C4a C5 . 1.538(3) y C4a C8a . 1.548(3) y C4a C9 . 1.548(3) y C5 C6 . 1.525(4) n C6 C7 . 1.503(4) n C7 O15 . 1.428(3) y C7 C8 . 1.525(4) n C8 C8a . 1.532(3) y C9 C10 . 1.516(4) n C11 C12 . 1.384(3) n C11 C12' . 1.384(3) n C12 C13 . 1.385(4) n C12' C13' . 1.386(4) n C13 C14 . 1.384(4) n C13' C14 . 1.381(4) n N1 H1 . 0.9103 ? C1' H1'A . 0.9800 ? C2 H2A . 0.9700 ? C2 H2B . 0.9700 ? C2' H2'A . 0.9600 ? C2' H2'B . 0.9600 ? C2' H2'C . 0.9600 ? C3 H3A . 0.9700 ? C3 H3B . 0.9700 ? C4 H4A . 0.9700 ? C4 H4B . 0.9700 ? C5 H5A . 0.9700 ? C5 H5B . 0.9700 ? C6 H6A . 0.9700 ? C6 H6B . 0.9700 ? C7 H7A . 0.9800 ? C8 H8A . 0.9700 ? C8 H8B . 0.9700 ? C8a H8AA . 0.9800 ? C9 H9A . 0.9700 ? C9 H9B . 0.9700 ? C10 H10A . 0.9600 ? C10 H10B . 0.9600 ? C10 H10C . 0.9600 ? C12 H12A . 0.9300 ? C12' H12B . 0.9300 ? C13 H13A . 0.9300 ? C13' H13B . 0.9300 ? C14 H14A . 0.9300 ? O15 H15 . 0.7429 ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_site_symmetry_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_publ_flag N1 H1 Br1 . 0.91 2.62 3.492(2) 161 yes O15 H15 Br1 1_565 0.74 2.75 3.491(3) 179 yes loop_ _geom_torsion_atom_site_label_1 _geom_torsion_atom_site_label_2 _geom_torsion_atom_site_label_3 _geom_torsion_atom_site_label_4 _geom_torsion _geom_torsion_publ_flag C2 N1 C1' C11 179.4(2) n C8a N1 C1' C11 -54.5(2) n C2 N1 C1' C2' 54.8(3) n C8a N1 C1' C2' -179.2(2) n C1' N1 C2 C3 -177.5(2) n C8a N1 C2 C3 56.1(3) n N1 C2 C3 C4 -53.1(3) n C2 C3 C4 C4a 52.8(3) n C3 C4 C4a C5 -172.6(2) n C3 C4 C4a C8a -54.0(3) n C3 C4 C4a C9 69.4(3) n C4 C4a C5 C6 66.6(3) n C8a C4a C5 C6 -52.7(3) n C9 C4a C5 C6 -175.0(2) n C4a C5 C6 C7 56.1(3) n C5 C6 C7 O15 -179.7(2) n C5 C6 C7 C8 -56.1(3) n O15 C7 C8 C8a -178.1(2) n C6 C7 C8 C8a 56.8(3) n C7 C8 C8a N1 -179.7(2) n C7 C8 C8a C4a -54.6(3) n C2 N1 C8a C8 67.6(2) n C1' N1 C8a C8 -59.0(2) n C2 N1 C8a C4a -58.9(2) n C1' N1 C8a C4a 174.51(18) n C4 C4a C8a C8 -68.7(3) n C5 C4a C8a C8 51.0(3) n C9 C4a C8a C8 170.3(2) n C4 C4a C8a N1 56.8(3) n C5 C4a C8a N1 176.54(18) n C9 C4a C8a N1 -64.1(2) n C4 C4a C9 C10 179.7(2) n C5 C4a C9 C10 60.5(3) n C8a C4a C9 C10 -59.0(3) n C2' C1' C11 C12 -101.5(3) n N1 C1' C11 C12 133.3(2) n C2' C1' C11 C12' 74.0(3) n N1 C1' C11 C12' -51.2(3) n C12' C11 C12 C13 -0.7(4) n C1' C11 C12 C13 174.9(3) n C12 C11 C12' C13' -0.6(4) n C1' C11 C12' C13' -176.1(2) n C11 C12 C13 C14 1.2(4) n C11 C12' C13' C14 1.5(4) n C12' C13' C14 C13 -1.0(4) n C12 C13 C14 C13' -0.3(4) n