#------------------------------------------------------------------------------ #$Date: 2025-08-19 12:52:15 +0100 (Tue, 19 Aug 2025) $ #$Revision: 301804 $ #$URL: svn://www.crystallography.net/cod/cif/2/21/42/2214244.cif $ #------------------------------------------------------------------------------ # # This file is available in the Crystallography Open Database (COD), # http://www.crystallography.net/. The original data for this entry # were provided by IUCr Journals, http://journals.iucr.org/. # # The file may be used within the scientific community so long as # proper attribution is given to the journal article from which the # data were obtained. # data_2214244 loop_ _publ_author_name 'Robinson, Tony V.' 'Taylor, Dennis K.' 'Tiekink, Edward R. T.' _publ_section_title (+)-(1R,2S,3S,4S)-2-Chloro-3-(phenylselanyl)cyclohexane-1,4-diol _journal_coeditor_code HG2241 _journal_issue 7 _journal_name_full 'Acta Crystallographica Section E' _journal_page_first o3350 _journal_page_last o3350 _journal_paper_doi 10.1107/S1600536807030851 _journal_volume 63 _journal_year 2007 _chemical_formula_iupac 'C12 H15 Cl O2 Se' _chemical_formula_moiety 'C12 H15 Cl O2 Se' _chemical_formula_sum 'C12 H15 Cl O2 Se' _chemical_formula_weight 305.65 _chemical_name_systematic ; (+)-(1R,2S,3S,4S)-2-Chloro-3-(phenylselanyl)cyclohexane-1,4-diol ; _space_group_IT_number 14 _symmetry_cell_setting monoclinic _symmetry_space_group_name_Hall '-P 2ybc' _symmetry_space_group_name_H-M 'P 1 21/c 1' _atom_sites_solution_hydrogens geom _atom_sites_solution_primary direct _atom_sites_solution_secondary difmap _audit_creation_method SHELXL-97 _cell_angle_alpha 90 _cell_angle_beta 95.4430(10) _cell_angle_gamma 90 _cell_formula_units_Z 4 _cell_length_a 13.5529(10) _cell_length_b 7.0627(5) _cell_length_c 12.9203(9) _cell_measurement_reflns_used 2654 _cell_measurement_temperature 223(2) _cell_measurement_theta_max 29.0 _cell_measurement_theta_min 2.3 _cell_volume 1231.16(15) _computing_cell_refinement 'SAINT (Bruker, 2000)' _computing_data_collection 'SMART (Bruker, 2000)' _computing_data_reduction SAINT _computing_molecular_graphics 'ORTEPII (Johnson, 1976) and DIAMOND (Brandenburg, 2006)' _computing_publication_material SHELXL97 _computing_structure_refinement 'SHELXL97 (Sheldrick, 1997)' _computing_structure_solution 'SIR92 (Altomare et al., 1994)' _diffrn_ambient_temperature 223(2) _diffrn_measured_fraction_theta_full 1.000 _diffrn_measured_fraction_theta_max 1.000 _diffrn_measurement_device_type 'Bruker SMART CCD' _diffrn_measurement_method \w _diffrn_radiation_monochromator graphite _diffrn_radiation_source 'fine-focus sealed tube' _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71069 _diffrn_reflns_av_R_equivalents 0.025 _diffrn_reflns_av_sigmaI/netI 0.029 _diffrn_reflns_limit_h_max 17 _diffrn_reflns_limit_h_min -17 _diffrn_reflns_limit_k_max 7 _diffrn_reflns_limit_k_min -9 _diffrn_reflns_limit_l_max 16 _diffrn_reflns_limit_l_min -14 _diffrn_reflns_number 8348 _diffrn_reflns_theta_full 27.5 _diffrn_reflns_theta_max 27.5 _diffrn_reflns_theta_min 1.5 _diffrn_standards_decay_% 0 _diffrn_standards_number 0 _exptl_absorpt_coefficient_mu 3.249 _exptl_absorpt_correction_T_max 1 _exptl_absorpt_correction_T_min 0.857 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details '(SADABS; Bruker, 2000)' _exptl_crystal_colour colourless _exptl_crystal_density_diffrn 1.649 _exptl_crystal_density_method 'not measured' _exptl_crystal_description block _exptl_crystal_F_000 616 _exptl_crystal_size_max 0.47 _exptl_crystal_size_mid 0.18 _exptl_crystal_size_min 0.16 _refine_diff_density_max 0.61 _refine_diff_density_min -0.31 _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.07 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 147 _refine_ls_number_reflns 2832 _refine_ls_number_restraints 0 _refine_ls_restrained_S_all 1.07 _refine_ls_R_factor_all 0.033 _refine_ls_R_factor_gt 0.029 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'calc w=1/[\s^2^(Fo^2^)+(0.0442P)^2^+0.3384P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.075 _refine_ls_wR_factor_ref 0.077 _reflns_number_gt 2524 _reflns_number_total 2832 _reflns_threshold_expression I>2\s(I) _cod_data_source_file hg2241.cif _cod_data_source_block I _cod_original_sg_symbol_H-M 'P 21/c' _cod_database_code 2214244 _cod_database_fobs_code 2214244 loop_ _symmetry_equiv_pos_as_xyz 'x, y, z' '-x, y+1/2, -z+1/2' '-x, -y, -z' 'x, -y-1/2, z-1/2' loop_ _atom_site_type_symbol _atom_site_label _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_calc_flag _atom_site_refinement_flags _atom_site_occupancy Se Se3 0.223073(15) 0.05198(3) 0.126906(17) 0.02977(9) Uani d . 1 Cl Cl2 0.26790(4) 0.52886(7) 0.17758(4) 0.03242(13) Uani d . 1 O O1 0.44699(11) 0.57891(19) 0.33447(12) 0.0285(3) Uani d . 1 H H1 0.4960 0.5419 0.3061 0.043 Uiso calc R 1 O O4 0.40103(11) -0.05964(19) 0.26849(13) 0.0302(3) Uani d . 1 H H4 0.4139 -0.1691 0.2890 0.045 Uiso calc R 1 C C1 0.38350(15) 0.4218(3) 0.34966(16) 0.0247(4) Uani d . 1 H H1A 0.3289 0.4669 0.3891 0.030 Uiso calc R 1 C C2 0.33780(14) 0.3428(3) 0.24551(15) 0.0220(4) Uani d . 1 H H2 0.3920 0.3041 0.2038 0.026 Uiso calc R 1 C C3 0.27180(14) 0.1719(3) 0.25939(15) 0.0232(4) Uani d . 1 H H3 0.2138 0.2144 0.2944 0.028 Uiso calc R 1 C C4 0.32598(15) 0.0194(3) 0.32663(17) 0.0264(4) Uani d . 1 H H4A 0.2783 -0.0814 0.3407 0.032 Uiso calc R 1 C C5 0.37069(17) 0.1005(3) 0.42939(17) 0.0314(4) Uani d . 1 H H5A 0.4083 0.0014 0.4689 0.038 Uiso calc R 1 H H5B 0.3173 0.1422 0.4702 0.038 Uiso calc R 1 C C6 0.43905(16) 0.2672(3) 0.41313(16) 0.0296(4) Uani d . 1 H H6A 0.4651 0.3184 0.4808 0.035 Uiso calc R 1 H H6B 0.4952 0.2238 0.3769 0.035 Uiso calc R 1 C C31 0.09343(14) 0.1616(3) 0.10249(16) 0.0270(4) Uani d . 1 C C32 0.06268(16) 0.2203(3) 0.00253(17) 0.0319(5) Uani d . 1 H H32 0.1073 0.2192 -0.0489 0.038 Uiso calc R 1 C C33 -0.03398(17) 0.2810(3) -0.02180(18) 0.0372(5) Uani d . 1 H H33 -0.0550 0.3189 -0.0901 0.045 Uiso calc R 1 C C34 -0.09930(17) 0.2861(3) 0.05327(19) 0.0374(5) Uani d . 1 H H34 -0.1647 0.3281 0.0366 0.045 Uiso calc R 1 C C35 -0.06820(17) 0.2291(4) 0.15351(19) 0.0412(6) Uani d . 1 H H35 -0.1124 0.2341 0.2053 0.049 Uiso calc R 1 C C36 0.02774(17) 0.1648(4) 0.17807(18) 0.0371(5) Uani d . 1 H H36 0.0481 0.1234 0.2459 0.045 Uiso calc R 1 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_12 _atom_site_aniso_U_13 _atom_site_aniso_U_23 Se3 0.02667(13) 0.02833(14) 0.03375(14) 0.00167(8) -0.00011(9) -0.00736(8) Cl2 0.0381(3) 0.0241(3) 0.0338(3) 0.0085(2) -0.0032(2) 0.0045(2) O1 0.0286(7) 0.0197(7) 0.0374(8) -0.0010(6) 0.0037(6) -0.0028(6) O4 0.0291(8) 0.0170(7) 0.0455(9) 0.0032(5) 0.0093(7) 0.0031(6) C1 0.0271(10) 0.0206(9) 0.0263(10) 0.0002(7) 0.0022(8) 0.0000(7) C2 0.0227(9) 0.0176(9) 0.0256(9) 0.0036(7) 0.0020(7) 0.0014(7) C3 0.0213(8) 0.0217(9) 0.0265(9) 0.0001(7) 0.0024(7) -0.0015(7) C4 0.0245(9) 0.0214(9) 0.0338(11) -0.0019(8) 0.0056(8) 0.0041(8) C5 0.0364(11) 0.0289(10) 0.0284(11) 0.0004(9) 0.0008(9) 0.0084(9) C6 0.0336(11) 0.0267(10) 0.0267(10) -0.0010(8) -0.0061(8) 0.0018(8) C31 0.0237(9) 0.0242(10) 0.0326(10) -0.0014(8) -0.0005(8) -0.0034(8) C32 0.0332(11) 0.0314(11) 0.0311(11) -0.0013(9) 0.0025(9) 0.0006(9) C33 0.0372(12) 0.0383(12) 0.0343(12) -0.0014(10) -0.0068(10) 0.0013(10) C34 0.0286(10) 0.0386(13) 0.0436(13) 0.0046(9) -0.0041(9) -0.0071(10) C35 0.0312(11) 0.0530(15) 0.0401(13) 0.0021(11) 0.0066(10) -0.0037(11) C36 0.0332(11) 0.0472(14) 0.0305(11) 0.0009(10) 0.0004(9) 0.0007(10) loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' Cl Cl 0.1484 0.1585 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' Se Se -0.0929 2.2259 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle C3 Se3 C31 101.31(8) C1 O1 H1 109.5 C4 O4 H4 109.5 O1 C1 C6 110.96(16) O1 C1 C2 111.13(16) C6 C1 C2 110.52(16) O1 C1 H1A 108.0 C6 C1 H1A 108.0 C2 C1 H1A 108.0 C3 C2 C1 112.21(16) C3 C2 Cl2 110.39(13) C1 C2 Cl2 108.25(13) C3 C2 H2 108.6 C1 C2 H2 108.6 Cl2 C2 H2 108.6 C2 C3 C4 111.71(15) C2 C3 Se3 113.03(13) C4 C3 Se3 107.17(13) C2 C3 H3 108.3 C4 C3 H3 108.3 Se3 C3 H3 108.3 O4 C4 C5 111.15(17) O4 C4 C3 107.65(16) C5 C4 C3 111.23(17) O4 C4 H4A 108.9 C5 C4 H4A 108.9 C3 C4 H4A 108.9 C4 C5 C6 111.59(17) C4 C5 H5A 109.3 C6 C5 H5A 109.3 C4 C5 H5B 109.3 C6 C5 H5B 109.3 H5A C5 H5B 108.0 C1 C6 C5 110.63(17) C1 C6 H6A 109.5 C5 C6 H6A 109.5 C1 C6 H6B 109.5 C5 C6 H6B 109.5 H6A C6 H6B 108.1 C32 C31 C36 119.85(19) C32 C31 Se3 117.70(16) C36 C31 Se3 122.11(16) C31 C32 C33 119.9(2) C31 C32 H32 120.0 C33 C32 H32 120.0 C34 C33 C32 120.4(2) C34 C33 H33 119.8 C32 C33 H33 119.8 C33 C34 C35 119.6(2) C33 C34 H34 120.2 C35 C34 H34 120.2 C36 C35 C34 120.4(2) C36 C35 H35 119.8 C34 C35 H35 119.8 C35 C36 C31 119.8(2) C35 C36 H36 120.1 C31 C36 H36 120.1 loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance Se3 C3 1.9669(19) Se3 C31 1.919(2) C2 Cl2 1.7990(19) C1 O1 1.429(2) O1 H1 0.8300 C4 O4 1.434(3) O4 H4 0.8300 C1 C6 1.521(3) C1 C2 1.532(3) C1 H1A 0.9900 C2 C3 1.523(3) C2 H2 0.9900 C3 C4 1.527(3) C3 H3 0.9900 C4 C5 1.518(3) C4 H4A 0.9900 C5 C6 1.525(3) C5 H5A 0.9800 C5 H5B 0.9800 C6 H6A 0.9800 C6 H6B 0.9800 C31 C32 1.383(3) C31 C36 1.383(3) C32 C33 1.386(3) C32 H32 0.9400 C33 C34 1.374(3) C33 H33 0.9400 C34 C35 1.383(3) C34 H34 0.9400 C35 C36 1.386(3) C35 H35 0.9400 C36 H36 0.9400 loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_site_symmetry_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_publ_flag O1 H1 O4 2_655 0.83 1.91 2.737(2) 174 y O4 H4 O1 1_545 0.83 1.91 2.744(2) 178 y loop_ _cod_related_entry_id _cod_related_entry_database _cod_related_entry_code 1 PubChem 139072480